【晴報專訊】肝癌治療現新曙光，港大開創全球首個「先縮後除」三部曲療法，成功將中期肝癌患者的腫瘤縮小，逾半人成功根治癌症。團隊指，過去70%患者因腫瘤過大、已入侵血管等原因，無法做手術，惟靠藥物或介入治療僅10%人能根治，痊癒形同「奇蹟」。若按全港每年1,800宗新症計算，新療法適用於當中500、600人，可望令200至300名患者根治癌症。
The first three types of "condensation before elimination" of liver cancer treatment in Hong Kong have succeeded in reducing the tumor in the medium term, with more than half of the population successfully treating cancer. The team says that the last 70% of the patients have been unable to operate because of tumors, invasive blood vessels, etc., and that only 10% of the patients can be treated with drugs or interventions, and the cure is like a miracle. If 1,800 new cases per year, the new treatment will be applied to 500-600 people, it is expected that 200-300 patients will be treated with cancer.
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左起：蔣子樑、陳智仁、溫應強
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港大外科學系臨床教授陳智仁指，研究在2019至2021年進行，有33名肝癌患者參與，其腫瘤直徑達5至17.5厘米，64%人已入侵大血管，無法即時用手術切除。
The study, carried out between 2019 and 2021, involved 33 patients with liver cancer with a tumor diameter of 5 to 17.5 centimetres, 64 per cent of whom had invaded large blood vessels and could not be removed by immediate surgery.
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團隊結合現有肝動脈栓塞化學療法（俗稱「大髀針」）、立體定向放射治療（電療）及免疫療法，患者治療半年後，31人腫瘤縮小，22人縮小幅度達30%。
The team combines a combination of hepatic arteries and chemotherapy (commonly known as the "big pin" ), stereodirectional radiotherapy (electrical) and immunotherapy. After six months of treatment, 31 people contracted their tumors and 22 fell by 30%.
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最終有18人適合做手術，當中14人因腫癌細胞完全壞死，只需定期觀察不用開刀，4人開刀後完全根治。
At the end of the day, 18 people were fit for surgery, and when 14 of them died of complete cancer, only regular observation was required, without the need for a knife, and 4 of them were treated completely after a knife had been opened.
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陳續指，三部曲治療後，患者存活中位數達30個月，較傳統用藥及介入治療的1年半至2年更長；局部控制率逾90%，較傳統40至50%更高。
It continues to be noted that after treatment of the three trajectories, the patient survives for 30 months, one and a half to two years longer than traditional drugs and interventions; local controls exceed 90 per cent, or 40 to 50 per cent more.
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有74歲男患者的腫瘤直徑8.4厘米，癌指數逾4,000，打大髀針及電療後縮小至4.5厘米，癌指數降至100，動手術切除後，癌指數跌至2，屬20以下的正常水平。
In 74-year-old male patients, the tumor had a diameter of 8.4 centimetres, the cancer count was over 4,000, the number of needles and electric treatments had been reduced to 4.5 centimetres, the number of cancers had dropped to 100 and the number of cancers had fallen to 2 after the surgery, at a normal level below 20.
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現年68歲的溫應強曾患前列腺癌，痊癒後再患肝癌，腫瘤直徑達13厘米，情況如「九死一生」，經治療後腫瘤完全壞死，癌指數跌至8，不用開刀已根治。
In the current year, 68-year-olds were suffering from prostate cancer, post-repair liver cancer, 13 centimetres of tumor diameter, as in the case of the "Nine Lives", the post-treatment tumor was completely broken and the cancer count dropped to eight, with no need to open a knife to cure it.
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副作用為炎症 類固醇可緩解
side effects are inflammation steroids can ease
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港大團隊指新療法創傷性低，僅打大髀針要留院1晚，其餘療程可即日來回。
The Hong Kong team refers to the low level of trauma associated with the new treatment, with only one night's stay in the hospital for the rest of the day.
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臨床腫瘤學系臨床助理教授蔣子樑補充，有關治療副作用包括皮膚發炎、肺炎及肝炎，但可用類固醇緩解，完成療程後炎症會消退。費用方面，公院已包大髀針及電療費，若非參與研究，整個免疫治療療程需自費約20至30萬元。
In terms of the cost, the public hospital has covered the cost of needles and electric therapy, and if not involved in the study, the entire course of immunization treatment costs approximately $200,000 to $300,000.
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轉載自: 晴報
etnet健康網購 | 6月限定優惠【送：明目藍莓精華36:1】乙樽? 火速行動
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